Large area, High Resolution SEM imaging of biological tissue network
The neuron – spanning many length scales
- Cell body – 4 to 100 mm in diameter
- Dendrites – 1 mm in diameter, a few 100 mm long.
- Axon – 1 mm in diameter, and sometimes 1+ meters long in humans!
- Myelin – 100 sheets, 10 nm pitch in sheath.
- Our brains have 86 billion neurons.
- Myelin is an electrical insulator, the degeneration of which is the cause of several neurological disorders, such as multiple sclerosis (MS).
Neurons make up the brain and spinal cord
Multiple stitched SEM images to form larger tissue region
Even larger stitched areas to show image entire organ
Different detectors display different intensity, contrast=> reveal useful information in bioimaging
